8β-ETHOXYEREMOPHIL-3,7(11)-DIENE-8α,12;6α,15-DIOLIDE

8β-Ethoxyeremophil-3,7(11)-diene-8α,12;6α,15-diolide

The title compound, C17H20O5, an eremophilane sesquiternoid, was isolated from the roots of Ligularia lapathifolia.The molecule contains four fused rings of which the six-membered ring A adopts a half-chair Doors conformation, the six-membered ring B adopts a chair conformation, the five-membered ring C is almost planar (r.m.s.deviation = 0.015Q

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Recent progress on the role and molecular mechanism of chicken ovalbumin upstream promoter-transcription factor II in cancer

Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) is an orphan receptor that regulates the expression of genes involved in development and homeostasis.COUP-TFII is also dysregulated in cancer, where it plays KAVA KAVA important roles in oncogenesis and malignant progression.Recent studies have also investigated altered microRN

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